Ernst Ruska Prize 2017Cryo-EM structure of haemoglobin at 3.2 Å determined with the Volta phase plate
With the advent of direct electron detectors, the perspectives of cryo-electron microscopy (cryo-EM) have changed in a profound way.
Figure 2. Hgb at 3.2 Å resolution. (a) The iron atom of the prosthetic haem group is coordinated by the proximal histidine residue, as evidenced by a strong density connecting them. (b) Side-chain details and putative water molecules in the 3D electron scattering potential map (red spheres).

