Ernst Ruska Prize 2017Cryo-EM structure of haemoglobin at 3.2 Å determined with the Volta phase plate
With the advent of direct electron detectors, the perspectives of cryo-electron microscopy (cryo-EM) have changed in a profound way.
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Figure 3. Resolution estimation. (a) Fourier shell correlation (FSC) plots indicating resolutions of 3.2 Å for the C2 symmetry (red line), 3.4 Å for the asymmetric (blue line) and 3.6 Å for the subset asymmetric (green line) reconstructions according to the FSC = 0.143 criterion. (b) Local resolution estimation of the C2 symmetry map. (c) Local resolution estimation of the asymmetric map.