LABO:
What are the key benefits of the TruePrime™ technology?

Pilar de la Huerta:
The resulting benefits of this innovative approach are enormous and include complete absence of common artifacts linked to the use of oligonucleotides. These nonspecific artifacts are amplified in the consecutive reaction and distort the final results or even can make it completely useless. Using our novel primer-free method, these primer induced errors do not even occur. Additional benefits include a reduced amplification bias in genome coverage compared to methods using random synthetic primers, a surpassing reliability as contaminating DNA is not amplified and an exquisite reproducibility when DNA is amplified from single mammalian cells. Moreover, TruePrime™ shows superior sensitivity, is easy to use and works perfectly well with all commonly used NGS platforms such as Illumina and Ion Torrent.

LABO:
The first products now on the market are TruePrime™ Single Cell WGA Kit and TruePrime™ WGA Kit. In which areas are these products being used?

Pilar de la Huerta:
Today, NGS is seen as the fastest-growing and most challenging segment in the genomics market. While still mostly used in research institutions, ongoing developments for higher throughput, increased accuracy, and cost efficiency as well as value creating data management will make NGS more and more attractive for commercial applications in clinical laboratories, hospitals and in pharma companies. Especially single cell analysis gets more and more attractive and has been named “Method of the year” by the renowned journal “Nature Methods” in 2013. The features of TruePrime™ make this product highly attractive for this type of analyses especially in life science areas such as human genetics, oncology, or pathology where researchers need to obtain biological information from the smallest amounts of samples down to single cells.

LABO:
You are planning to expand the TruePrime™ product family with further applications. When can we expect the next products to be launched?

Pilar de la Huerta:
We are currently developing a number of additional kits for our TruePrime™ product line as well as for other technologies for a multitude of applications for use with various DNA and RNA species that are expected to be launched throughout 2015 and 2016.

LABO:
How do you market your own products and how can researchers buy them?

Pilar de la Huerta:
Our own products are globally commercialized mainly through distributors as well as through Sygnis’ newly introduced TruePrime™ online shop under www.sygnis.com/shop. In addition, we have started intensive promotional marketing activities including a special TruePrime™ webinar hosted by the inventor of this technology and scientific board member of Sygnis, Prof. Luis Blanco on March 18th at 10:00AM EST which will be accessible from our homepage. You’re cordially invited!